Pūnaehana Hoʻolaha Laʻau (Lipid, Polymers, Hybrids)
Hoʻokumu mākou i nā ʻano hui like ʻole ma o kā mākou hui a me nā ʻenehana, a hana i nā haʻawina piha a hui pū me ka noiʻi hoʻomaʻamaʻa: hoʻomohala ʻana i ka ʻōnaehana lawe lāʻau me nā API i makemake ʻia e like me mRNA, DNA, siRNA, Antibodies, Proteins, Peptides a me nā Molecules Liʻiliʻi ʻē aʻe: Characterization, a Nā lawelawe hoʻāʻo, hui hui a me nā hoʻomohala kākoʻo aupuni (ʻo ia hoʻi SBIR/STTR)
Ka Ho'āʻo Analytical, Characterization, Assay Development
Hoʻopiha i ka Analytical Custom Testing (GMP a me Non-GMP) a me nā ʻano i hoʻomohala ʻia no ka hoʻomohala ʻana i ka lāʻau lapaʻau mua, ka hoʻāʻo ʻana, nā hoʻomohala ʻana a me ka hoʻololi ʻana i nā ʻenehana, piha piha analytical a me nā hoʻomohala ʻana e like me: Nanoparticle Size, Charge, Encapsulation Efficiency, Purity, Morphology, Residual ʻO Solvent, ka wela hoʻololi, ka nānā ʻike maka, a me ka microscopic.
Hoʻomohala Preclinical Formulation a me nā Laʻana
Hiki a me nā haʻawina piha, Nanoparticle Drug Delivery System Development (Preclinical Synthesis and Analytics), Including Ionizable and Cationic Lipid Nanoparticles a me Polymeric and Hybrid Lipid Nanoparticles, Optimization, Characterization, Toxicity, Effectiveness, Analytical Methods, and Formulation Manufacturing Process, Small Scale Manufacturing Process. Technology TransferPreclinical Formulation Synthesis, Optimization, Manufacturing Process, Drug Delivery Systems and Nanomedicines Development
Hoʻomohala Hana Hana (GMP)
Hāʻawi ʻo T&T Scientific i nā ʻano like ʻole a me ka ʻoiaʻiʻo o nā kaʻina hana hana āpau i hoʻohana ʻia no ka hana ʻana i nā huahana lāʻau Nanoparticle e like me Gene Therapies, a me nā Vaccines. No ka inoa. He Kakaikahi keia mau Kaʻina Hana: Ethanol Injection a Solvent Injection, Thin Film Hydration, Extrusion, Homogenization, Microfluidics and Sonication (Bath, Tip and Continuous).
Hoʻomohala ʻana i nā ʻano analytical (Papa piha, hōʻike, hōʻike)
Ma T&T Scientific, Hāʻawi mākou i ka Panel Analytical cGMP e pono ai no ka mana maikaʻi o ka Nanoparticle Drug Products e like me: Nanoparticle Size, Charge, Encapsulation Efficiency, Purity, Morphology, Residual Solvent, Transition Temperature, Visual Inspections, Targeting and Endosomal Scape Nā waiwai a me ka Microscopic. Ua hoʻokumu pū mākou i mau hoa no nā hoʻokolohua lapaʻau a me nā haʻawina holoholona.
cGMP Clinical and Commercial Batch Manufacturing, Hoʻopiha a hoʻopau
Hoʻopau ʻo T&T Scientific i ka hana GMP ma lalo o hoʻokahi hale a ua hoʻopaʻa ʻia ʻo ia ma mua o 5 mau manawa. Lawe ʻo T&T Scientific Corporation's Quality Management System i ke alakaʻi mai 21 CFR Part 820 Quality System Regulations a hoʻokō i nā koi kānāwai FDA GMP āpau. Aia kēia mau koi i ka 21 CFR Part 210, 21 CFR Part 211, a me 21 CFR Part 11. ʻAʻole koi ka hui i ka wehe ʻana mai ka 21 CFR Part 820, 201, 211, 11 ma 7140 Regal Lane, Knoxville, TN 37918.
Nā ʻenehana Hana Hana Solvent
ʻO nā ʻenehana Solvent Injection He Hoʻokomo ʻia ʻo ka Lipid Solution (I loko o ka Ethanol a i ʻole Diethyl Ether) i loko o kahi ʻano wai me ka lāʻau a me ka hoʻopaʻa. ʻO nā ʻano hana hoʻoheheʻe ʻia i loko o ka hoʻoheheʻe ʻana o ka lipid i kahi mea hoʻoheheʻe organik a me ka hoʻokomo ʻana o ka hopena i loko o ka pae wai. ʻElua mau mea hoʻoheheʻe nui (Ethanol a me Etera) i hoʻohana ʻia no ka hoʻomākaukau ʻana i ka Liposomal Nanoformulation. Hāʻawi ʻo T&T Scientific i ke kahua maikaʻi loa o ka honua no ka Scalable, GMP, hoʻomalu a pololei i ka hana ʻana o nā huahana lāʻau Nanoparticle ma kahi ʻanuʻu hoʻokahi.
Liposome Extrusion Manufacturing Technologies
Hoʻohana ʻia nā ʻenehana hoʻopau liposome no ka hoʻopaʻa pololei ʻana i nā nanoparticles lipid, liposomes, lipoplexes, niosomes a me nā huahana lāʻau lāʻau lāʻau Nano-scale a me nā ʻōnaehana lawe lāʻau. Hāʻawi ʻo T&T Scientific i ka hoʻohana mua ʻana o ka honua i ka Lipid a me Liposome Extrusion System e ʻae ai i ka wikiwiki, maʻalahi, ʻaʻohe contamination, a me ke kiʻekiʻe o ka hana ʻana o kēia mau huahana lāʻau Nanomedicine me ka PDI ma lalo o 0.05-0.07.
Pūnaehana Hoʻolaha Laʻau (Lipid, Polymer, Hybrids)
Hāʻawi ʻia ʻo T&T Scientific:
1) Mākaukau-e hoʻohana i nā huahana a me nā kime e like me Lipid, Polymers a me Hybrid Nanoparticles
2) Ma lalo o ka hoʻomohala ʻana a me ka loiloi ʻana i nā Nanoparticles i hana ʻia e nā lipid (Cationic, Ionizable, a me Neutral), Polymers, a me Hybrid e komo ana i nā ʻano like ʻole o nā lipid a me nā polymers.
CDMO &
Papahana ʻenehana
no nā ʻōnaehana lawe lāʻau
& Nanomedicines
CDMO i kakau inoa FDA
Pūnaehana hoʻokele maikaʻi cGMP uila
Hoʻokō i ke kānāwai Federal
21 CFR Mahele 210, 211, a me 21, 11 no
Hoʻomohala lāʻau lapaʻau
a me ka Hana Hana
ʻenehana hana
Laboratory & GMP
Hoʻohui piha ʻia me
Akamai ʻimi hoʻopunipuni a
Hiki ke aʻo mīkini
ʻO ka unuhi ʻana o nā lāʻau lapaʻau mai ka Lab a i nā maʻi maʻi
Pūnaehana Hoʻolaha Laʻau (Lipid, Polymers, Hybrids)
Hoʻokumu mākou i nā ʻano hui like ʻole ma o kā mākou hui a me nā ʻenehana, a hana i nā haʻawina piha a hui pū me ka noiʻi hoʻomaʻamaʻa: hoʻomohala ʻana i ka ʻōnaehana lawe lāʻau me nā API i makemake ʻia e like me mRNA, DNA, siRNA, Antibodies, Proteins, Peptides a me nā Molecules Liʻiliʻi ʻē aʻe: Characterization, a Nā lawelawe hoʻāʻo, hui hui a me nā hoʻomohala kākoʻo aupuni (ʻo ia hoʻi SBIR/STTR)
Ka Ho'āʻo Analytical, Characterization, Assay Development
Hoʻopiha i ka Analytical Custom Testing (GMP a me Non-GMP) a me nā ʻano i hoʻomohala ʻia no ka hoʻomohala ʻana i ka lāʻau lapaʻau mua, ka hoʻāʻo ʻana, nā hoʻomohala ʻana a me ka hoʻololi ʻana i nā ʻenehana, piha piha analytical a me nā hoʻomohala ʻana e like me: Nanoparticle Size, Charge, Encapsulation Efficiency, Purity, Morphology, Residual ʻO Solvent, ka wela hoʻololi, ka nānā ʻike maka, a me ka microscopic.
Hoʻomohala Preclinical Formulation a me nā Laʻana
Hiki a me nā haʻawina piha, Nanoparticle Drug Delivery System Development (Preclinical Synthesis and Analytics), Including Ionizable and Cationic Lipid Nanoparticles a me Polymeric and Hybrid Lipid Nanoparticles, Optimization, Characterization, Toxicity, Effectiveness, Analytical Methods, and Formulation Manufacturing Process, Small Scale Manufacturing Process. Technology TransferPreclinical Formulation Synthesis, Optimization, Manufacturing Process, Drug Delivery Systems and Nanomedicines Development
Hoʻomohala Hana Hana (GMP)
Hāʻawi ʻo T&T Scientific i nā ʻano like ʻole a me ka ʻoiaʻiʻo o nā kaʻina hana hana āpau i hoʻohana ʻia no ka hana ʻana i nā huahana lāʻau Nanoparticle e like me Gene Therapies, a me nā Vaccines. No ka inoa. He Kakaikahi keia mau Kaʻina Hana: Ethanol Injection a Solvent Injection, Thin Film Hydration, Extrusion, Homogenization, Microfluidics and Sonication (Bath, Tip and Continuous).
Hoʻomohala ʻana i nā ʻano analytical (Papa piha, hōʻike, hōʻike)
Ma T&T Scientific, Hāʻawi mākou i ka Panel Analytical cGMP e pono ai no ka mana maikaʻi o ka Nanoparticle Drug Products e like me: Nanoparticle Size, Charge, Encapsulation Efficiency, Purity, Morphology, Residual Solvent, Transition Temperature, Visual Inspections, Targeting and Endosomal Scape Nā waiwai a me ka Microscopic. Ua hoʻokumu pū mākou i mau hoa no nā hoʻokolohua lapaʻau a me nā haʻawina holoholona.
cGMP Clinical and Commercial Batch Manufacturing, Hoʻopiha a hoʻopau
Hoʻopau ʻo T&T Scientific i ka hana GMP ma lalo o hoʻokahi hale a ua hoʻopaʻa ʻia ʻo ia ma mua o 5 mau manawa. Lawe ʻo T&T Scientific Corporation's Quality Management System i ke alakaʻi mai 21 CFR Part 820 Quality System Regulations a hoʻokō i nā koi kānāwai FDA GMP āpau. Aia kēia mau koi i ka 21 CFR Part 210, 21 CFR Part 211, a me 21 CFR Part 11. ʻAʻole koi ka hui i ka wehe ʻana mai ka 21 CFR Part 820, 201, 211, 11 ma 7140 Regal Lane, Knoxville, TN 37918.
Nā ʻenehana Hana Hana Solvent
ʻO nā ʻenehana Solvent Injection He Hoʻokomo ʻia ʻo ka Lipid Solution (I loko o ka Ethanol a i ʻole Diethyl Ether) i loko o kahi ʻano wai me ka lāʻau a me ka hoʻopaʻa. ʻO nā ʻano hana hoʻoheheʻe ʻia i loko o ka hoʻoheheʻe ʻana o ka lipid i kahi mea hoʻoheheʻe organik a me ka hoʻokomo ʻana o ka hopena i loko o ka pae wai. ʻElua mau mea hoʻoheheʻe nui (Ethanol a me Etera) i hoʻohana ʻia no ka hoʻomākaukau ʻana i ka Liposomal Nanoformulation. Hāʻawi ʻo T&T Scientific i ke kahua maikaʻi loa o ka honua no ka Scalable, GMP, hoʻomalu a pololei i ka hana ʻana o nā huahana lāʻau Nanoparticle ma kahi ʻanuʻu hoʻokahi.
Liposome Extrusion Manufacturing Technologies
Hoʻohana ʻia nā ʻenehana hoʻopau liposome no ka hoʻopaʻa pololei ʻana i nā nanoparticles lipid, liposomes, lipoplexes, niosomes a me nā huahana lāʻau lāʻau lāʻau Nano-scale a me nā ʻōnaehana lawe lāʻau. Hāʻawi ʻo T&T Scientific i ka hoʻohana mua ʻana o ka honua i ka Lipid a me Liposome Extrusion System e ʻae ai i ka wikiwiki, maʻalahi, ʻaʻohe contamination, a me ke kiʻekiʻe o ka hana ʻana o kēia mau huahana lāʻau Nanomedicine me ka PDI ma lalo o 0.05-0.07.
Pūnaehana Hoʻolaha Laʻau (Lipid, Polymer, Hybrids)
Hāʻawi ʻia ʻo T&T Scientific:
1) Mākaukau-e hoʻohana i nā huahana a me nā kime e like me Lipid, Polymers a me Hybrid Nanoparticles
2) Ma lalo o ka hoʻomohala ʻana a me ka loiloi ʻana i nā Nanoparticles i hana ʻia e nā lipid (Cationic, Ionizable, a me Neutral), Polymers, a me Hybrid e komo ana i nā ʻano like ʻole o nā lipid a me nā polymers.
CDMO &
Papahana ʻenehana
no nā ʻōnaehana lawe lāʻau a me nā Nanomedicines
CDMO i kakau inoa FDA
Pono ka ʻōnaehana hoʻokele maikaʻi cGMP uila me
ka Federal Regulation 21 CFR Part 210, 211, a me 21, 11
no ka hoʻomohala lāʻau lapaʻau
a me ka Hana Hana
ʻenehana hana
Laboratory & GMP
Hoʻohui piha ʻia me
Akamai ʻimi hoʻopunipuni a
Hiki ke aʻo mīkini
ʻO ka unuhi ʻana o nā lāʻau lapaʻau mai ka Lab a i nā maʻi maʻi
Pūnaehana Hoʻolaha Laʻau (Lipid, Polymers, Hybrids)
Hoʻokumu mākou i nā ʻano hui like ʻole ma o kā mākou hui a me nā ʻenehana, a hana i nā haʻawina piha a hui pū me ka noiʻi hoʻomaʻamaʻa: hoʻomohala ʻana i ka ʻōnaehana lawe lāʻau me nā API i makemake ʻia e like me mRNA, DNA, siRNA, Antibodies, Proteins, Peptides a me nā Molecules Liʻiliʻi ʻē aʻe: Characterization, a Nā lawelawe hoʻāʻo, hui hui a me nā hoʻomohala kākoʻo aupuni (ʻo ia hoʻi SBIR/STTR)
Ka Ho'āʻo Analytical, Characterization, Assay Development
Hoʻopiha i ka Analytical Custom Testing (GMP a me Non-GMP) a me nā ʻano i hoʻomohala ʻia no ka hoʻomohala ʻana i ka lāʻau lapaʻau mua, ka hoʻāʻo ʻana, nā hoʻomohala ʻana a me ka hoʻololi ʻana i nā ʻenehana, piha piha analytical a me nā hoʻomohala ʻana e like me: Nanoparticle Size, Charge, Encapsulation Efficiency, Purity, Morphology, Residual ʻO Solvent, ka wela hoʻololi, ka nānā ʻike maka, a me ka microscopic.
Hoʻomohala Preclinical Formulation a me nā Laʻana
Hiki a me nā haʻawina piha, Nanoparticle Drug Delivery System Development (Preclinical Synthesis and Analytics), Including Ionizable and Cationic Lipid Nanoparticles a me Polymeric and Hybrid Lipid Nanoparticles, Optimization, Characterization, Toxicity, Effectiveness, Analytical Methods, and Formulation Manufacturing Process, Small Scale Manufacturing Process. Technology TransferPreclinical Formulation Synthesis, Optimization, Manufacturing Process, Drug Delivery Systems and Nanomedicines Development
Hoʻomohala Hana Hana (GMP)
Hāʻawi ʻo T&T Scientific i nā ʻano like ʻole a me ka ʻoiaʻiʻo o nā kaʻina hana hana āpau i hoʻohana ʻia no ka hana ʻana i nā huahana lāʻau Nanoparticle e like me Gene Therapies, a me nā Vaccines. No ka inoa. He Kakaikahi keia mau Kaʻina Hana: Ethanol Injection a Solvent Injection, Thin Film Hydration, Extrusion, Homogenization, Microfluidics and Sonication (Bath, Tip and Continuous).
Hoʻomohala ʻana i nā ʻano analytical (Papa piha, hōʻike, hōʻike)
Ma T&T Scientific, Hāʻawi mākou i ka Panel Analytical cGMP e pono ai no ka mana maikaʻi o ka Nanoparticle Drug Products e like me: Nanoparticle Size, Charge, Encapsulation Efficiency, Purity, Morphology, Residual Solvent, Transition Temperature, Visual Inspections, Targeting and Endosomal Scape Nā waiwai a me ka Microscopic. Ua hoʻokumu pū mākou i mau hoa no nā hoʻokolohua lapaʻau a me nā haʻawina holoholona.
cGMP Clinical and Commercial Batch Manufacturing, Hoʻopiha a hoʻopau
Hoʻopau ʻo T&T Scientific i ka hana GMP ma lalo o hoʻokahi hale a ua hoʻopaʻa ʻia ʻo ia ma mua o 5 mau manawa. Lawe ʻo T&T Scientific Corporation's Quality Management System i ke alakaʻi mai 21 CFR Part 820 Quality System Regulations a hoʻokō i nā koi kānāwai FDA GMP āpau. Aia kēia mau koi i ka 21 CFR Part 210, 21 CFR Part 211, a me 21 CFR Part 11. ʻAʻole koi ka hui i ka wehe ʻana mai ka 21 CFR Part 820, 201, 211, 11 ma 7140 Regal Lane, Knoxville, TN 37918.
Nā ʻenehana Hana Hana Solvent
ʻO nā ʻenehana Solvent Injection He Hoʻokomo ʻia ʻo ka Lipid Solution (I loko o ka Ethanol a i ʻole Diethyl Ether) i loko o kahi ʻano wai me ka lāʻau a me ka hoʻopaʻa. ʻO nā ʻano hana hoʻoheheʻe ʻia i loko o ka hoʻoheheʻe ʻana o ka lipid i kahi mea hoʻoheheʻe organik a me ka hoʻokomo ʻana o ka hopena i loko o ka pae wai. ʻElua mau mea hoʻoheheʻe nui (Ethanol a me Etera) i hoʻohana ʻia no ka hoʻomākaukau ʻana i ka Liposomal Nanoformulation. Hāʻawi ʻo T&T Scientific i ke kahua maikaʻi loa o ka honua no ka Scalable, GMP, hoʻomalu a pololei i ka hana ʻana o nā huahana lāʻau Nanoparticle ma kahi ʻanuʻu hoʻokahi.
Liposome Extrusion Manufacturing Technologies
Hoʻohana ʻia nā ʻenehana hoʻopau liposome no ka hoʻopaʻa pololei ʻana i nā nanoparticles lipid, liposomes, lipoplexes, niosomes a me nā huahana lāʻau lāʻau lāʻau Nano-scale a me nā ʻōnaehana lawe lāʻau. Hāʻawi ʻo T&T Scientific i ka hoʻohana mua ʻana o ka honua i ka Lipid a me Liposome Extrusion System e ʻae ai i ka wikiwiki, maʻalahi, ʻaʻohe contamination, a me ke kiʻekiʻe o ka hana ʻana o kēia mau huahana lāʻau Nanomedicine me ka PDI ma lalo o 0.05-0.07.
Pūnaehana Hoʻolaha Laʻau (Lipid, Polymer, Hybrids)
Hāʻawi ʻia ʻo T&T Scientific:
1) Mākaukau-e hoʻohana i nā huahana a me nā kime e like me Lipid, Polymers a me Hybrid Nanoparticles
2) Ma lalo o ka hoʻomohala ʻana a me ka loiloi ʻana i nā Nanoparticles i hana ʻia e nā lipid (Cationic, Ionizable, a me Neutral), Polymers, a me Hybrid e komo ana i nā ʻano like ʻole o nā lipid a me nā polymers.
CDMO &
Papahana Hoʻololi ʻenehana
no nā ʻōnaehana lawe lāʻau a me nā Nanomedicines
mai Preclinical a i Kalepa
Lakoʻo Scalable & Hoʻomau
Nā ʻenehana hana GMP
Hoʻopili piha ʻia me ka naʻauao Artificial
a me nā mana aʻo mīkini
CDMO i kakau inoa FDA
me Electronic cGMP Quality Management System
Hoʻokō piha i nā alakaʻi Federal o
21 CFR Māhele 210, 211, a me 11 no ka lāʻau lapaʻau
Hoʻomohala a me ka hana ʻana
Nā Pūnaehana Hoʻouna Lipid-Based i ka hoʻomohala ʻana i nā maʻi maʻi Genetic a me Subunit
Hoʻokumu ʻia nā mea lawe lipidic me nā mea kūlohelohe, synthetic, a i ʻole physiological lipid/phospholipid.
ʻO ka maikaʻi o nā kūlana mālama no ka lipid nanoparticle-formulated self-replicating RNA vaccines
ʻO kekahi o nā hoʻokolohua mua ma ka lawe ʻana i nā molekole RNA mai ka makahiki 1978, i ka wā i hoʻololi ʻia ai nā lymphocytes ʻiole in vitro me ka mRNA encoding rabbit globin me ka hoʻohana ʻana i nā liposomes.
Ka palena a me nā pilikia o ka hāʻawi ʻana i ka mRNA e pili ana i ka nanoparticle i ka mālama ʻana i ka maʻi kanesa
He ʻōlelo kū hoʻokahi a transient ka mRNA e hoʻohaʻahaʻa i ka hopena o ka mutagenesis insertional. Mai ka loaʻa ʻana o ka mRNA i kākau ʻia in vitro, ua loaʻa i ka synthetic mRNA ka hoihoi nui mai nā ʻano biology, lāʻau lapaʻau, a me nā ʻepekema ʻepekema waiwai.
ʻO Taylor Dispersion Analysis e kākoʻo i ka hoʻokumu ʻana o ka lipid-nanoparticle no nā kano mRNA
ʻO Lipid nanoparticles (LNPs) i kēia manawa nā ʻōnaehana hoʻouna ʻo ribonucleic acid (mRNA).
Ka hāʻawi ʻana i ka uku a me ka hiki o ka mRNA lipid nanoparticles
Lipid nanoparticles (LNPs) he mau kaʻa maikaʻi e hoʻopuka i nā lāʻau lapaʻau mRNA a me nā lāʻau lapaʻau. He mea paʻakikī ke loiloi i nā hiʻohiʻona mRNA packaging ....
RNA Circular: He palena e kū mai ana i nā pahuhopu therapeutic RNA, RNA therapeutics, a me nā lāʻau lapaʻau mRNA
ʻO nā RNA pōʻai (circular) kahi papa o ka RNA kūlohelohe (biogenic) a i ʻole synthetic pani ʻia me ka ʻole o 5' a i ʻole 3' hopena......
Hoʻopili piha i ka maʻi oncolytic me ka hoʻohana ʻana i nā membrane erythroctye-liposome hybrid no ka hoʻonui ʻana i ka hopena anti-refractory tumor.
ʻO Lipid nanoparticles (LNPs) i kēia manawa nā ʻōnaehana hoʻouna ʻo ribonucleic acid (mRNA).
Lipid Nanoparticles─Mai nā Liposomes a i ka MRNA Vaccine Delivery, kahi ʻāina o ka noiʻi ʻokoʻa a me ka holomua.
Ka hopena o nā antibodies anti-PEG i hoʻoulu ʻia e nā maʻi maʻi SARS-CoV-2 mRNA
No ke aha i pōkole loa ai nā hoʻokumu ʻana o ka mRNA-ionizable LNPs: nā kumu a me nā ala i waho
I ka hala ʻana o ka manawa, hoʻohaʻahaʻa ka nui o ka ethanol i ka membrane lipid, e hana ʻole ai ka hoʻokumu ʻana.
Albert Einstein
Kauka
"ʻOi aku ka nui o ka noʻonoʻo ma mua o ka ʻike. Ua kaupalena ʻia ka ʻike. Hoʻopuni ka noʻonoʻo i ka honua.... ʻO ka mea nui ʻaʻole e hoʻōki i ka nīnau ʻana. Aia ke kumu o ka ʻimi no ka noho ʻana.... Ua like ke ola me ka holo kaʻa. kaulike, pono ʻoe e hoʻomau i ka neʻe ʻana.
Thomas Edison
Mea'ike
"Mai hoʻonāwaliwali inā hāʻule ʻoe. E aʻo mai ia mea. E hoʻomau i ka hoʻāʻo ʻana.... ʻAʻole au i hāʻule. Ua loaʻa iaʻu he 10,000 mau ala e hana ʻole ai.... ʻO ka hoʻomaha ʻole ka ʻoluʻolu a ʻo ka hōʻoluʻolu ka mea pono mua o ka holomua. . E hoike mai oe ia'u i kanaka oluolu loa, a e hoike aku au ia oe i ka hemahema."
ʻO Bob Langer
MIT - Harvard
"E paipai i nā haumāna e hana i nā papahana hopena kiʻekiʻe e hiki ke hoʻololi i ka honua. Mai ʻōlelo ʻoe ʻaʻole hiki ke hana kēia manaʻo. E hahai wale i kou puʻuwai. E koho i kahi mea āu e manaʻo ai e aloha ana ʻoe. Ua hoʻāʻo wau e hoʻomohala i kahi polymer hoʻokuʻu ʻia a me nā mea. ʻAʻole i hana maikaʻi. He mau haneli ala hiki ke noʻonoʻo e pili ana i ka hana ʻana i kēia... Ua kōkua koʻu intuition e alakaʻi iaʻu i kahi ala e hana ai."
Steve Jobs
Apple
"Manaʻo ka poʻe ʻo ka manaʻo noʻonoʻo ʻo ia ka ʻōlelo ʻae i ka mea āu e noʻonoʻo ai. ʻO nā manaʻo e hoʻomaloʻo i kou leo ponoʻī ... I kekahi manawa e paʻi ke ola iā ʻoe i ke poʻo me ka pōhaku.
Jack Ma
ʻO ka hui Alibaba
"Inā ʻaʻole ʻoe e haʻalele, loaʻa iā ʻoe ka manawa. ʻO ka hāʻawi ʻana ʻo ia ka hāʻule nui loa. Ua hāʻule wau i nā mea ʻakaʻaka: ʻo ka hoʻokolohua kula kumu nui no ʻelua manawa, ʻekolu manawa ma ke kula waena, ua noi au no Harvard, no 10 mau manawa. , hōʻole, noi au no KFC i ka hiki ʻana i Kina. 24 poʻe i hele mai no ka hana, 23 i loaʻa. ʻO wau wale nō ka mea ʻaʻole.
ʻO Jeff Bezos
Amazon
"Inā hiki iā mākou ke hoʻomau i kā mākou mau mea hoʻokūkū e kālele ana iā mākou ʻoiai mākou e noʻonoʻo nei i ka mea kūʻai aku, i ka hopena e hoʻololi mākou i ka maikaʻi ... ʻO ka mea pōʻino ʻaʻole e ulu. ʻO ka wahi maikaʻi loa o ka honua e hāʻule ai a ʻaʻole hoʻi a me nā mea i hana ʻia he mau māhoe hiki ʻole ke hoʻokaʻawale ʻia. noho ʻoihana."
Unuhi i ka Novel Nanomedicines i Impact mai ka Lab i nā maʻi
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